研究業績 (Publications)


Saito, S. and Uozumi, N.
Guard cell membrane anion transport systems and their regulatory components: an eleborate mechanism controlling stress-induced stomatal closure
Plants 8, 9 (2019)

Adams, E., Miyazaki, T., Saito, S., Uozumi, N. and Shin, R.
Cesium inhibits plant growth primarily through reduction of potassium influx and accumulation in Arabidopsis
Plant Cell Physiol. 60 (1), 63-76 (2019)

Saito, S., Hamamoto, S., Moriya, K., Matsuura, A., Sato, Y., Muto, J., Noguchi, H., Yamauchi, S., Tozawa, Y., Ueda, M., Hashimoto, K., Köster, P. Qiuyan. D., Held, K., Kudla, J., Utsumi, T. and Uozumi, N.
N-myristoylation and S-acylation are common modifications of Ca2+ regulated Arabidopsis kinases and are required for activation of the SLAC1 anion channel
New Phytol. 218, 1504-1521 (2018)

Hamamoto, S., Mori, Y., Yabe, I. and Uozumi,N.
In vitro and in vivo characterization of modulation of the vacuolar cation channel TRPY1 from Saccharomyces cerevisiae
FEBS J. 285, 1146–1161 (2018)

Kera, K., Nagyama, T., Nanatani, K., Saeki-Yamoto, C., Tominaga, A., Souma, S., Miura, N., Takeda, K., Kayamori, S., Ando, E., Higashi, K., Igarashi, K. and Uozumi, N.
Reduction of spermidine content resulting from inactivation of two arginine decarboxylases increases biofilm formation in Synechocystis sp. PCC 6803
J. Bacteriol. 200 (9), E00664-17 (2018)


Oikawa, T., Ishimaru, Y., Munemasa, S., Takeuchi, Y., Washiyama, K. Hamamoto, S., Yoshikawa, N., Mutara, Y., Uozumi, N. and Ueda, M.
Ion channels regulate nyctinastic leaf opening in Samanea saman.
Current Biology 28, 2230–2238 (2018)

Chang,D., Sakuma, S., Kera, K., Uozumi, N. and Arai F.
Measurement of mechanical properties of single Synechocystis sp. strain PCC6803 cells in different osmotic concentrations using robot integrated microfluidic chip
Lab Chip 18, 1241-1249 (2018)

Toh, S., Inoue, S., Toda Y., Yuki, T., Suzuki, K., Hamamoto, S., Fukatsu, K., Aoki, S., Uchida, M., Asai, E., Uozumi, N., Ayato S. and Kinoshita, T.
Identification and characterization of compounds that affect stomatal movements
Plant Cell Physiol. 59, 1568-1580 (2018)

Saito, S., Hoshi, N., Zulkifli, L., Widyastutib, S, Goshima, S., Dreyer, I. and Uozumi, N.
Identification of regions responsible for the function of the plant K+ channels KAT1 and AKT2 in Saccharomyces cerevisiae and Xenopus laevis oocytes
Channels, 11, 510-516 (2017)

Ishimaru, Y., Washiyama, K. Oikawa, T. Hamamoto, S. Uozumi, N. and Ueda, M.
Dimerization of GTR1 regulates their plasmamembrane localization.
Plant Signal. Behav. e1334749, 12, (6) (2017)

Tatsumi, D., Nanatani, K., Koike, Y., Kamagata, K., Takahashi, S., Konno, A., Furuta, T., Sakurai, M. and Uozumi, N.
Probing native metal ion association sites through quenching of fluorophores in the nucleotide binding domains of the ABC transporter MsbA.
Biochem. J. 474, 1993-2007 (2017)
ABCトランスポーターのモデル輸送体MsbAには,重金属(Ni Cu)が配位する部位が存在する.

Tanudjaja, Ellen, Hoshi, N., Su, Y-S., Hamamoto, S. and Uozumi, N.
Kup-mediated Cs+ uptake and Kdp-driven K+ uptake coordinate to promote cell growth during excess Cs+ conditions in Escherichia coli
Sci. Rep. 7, 2122 (2017)

Ishimaru, Y., Oikawa, T., Suzuki, T., Takeishi, S., Matsuura, H., Takahashi, K., Hamamoto, S., Uozumi, N., Shimizu, T., Seo, M., Ohta, H., and Ueda, M.
GTR1 is a jasmonic acid and jasmonoyl-l-isoleucine transporter in Arabidopsis thaliana.
Biosci. Biotech. Biochem. 81, 249-255 (2017)

Takito, J., Ota, M., Oba, C., Fujiwara, H., Murata, K., Yamaguchi, K., Uozumi, N., Nakamura, M., Inomata, H. and Ohizumi, Y.
Limonene enhances the cAMP response element (CRE)-dependent transcriptional activity activated via adenosine A2A receptor in a neural-crest derived cell line, PC-12
Planta Medica International Open, 3, e60-e62 (2016)

Mishima, E., Sato, Y., Nanatani, K., Hoshi, N., Lee, J-K., Schiller, N., von Heijne, G., Sakaguchi, M., and Uozumi, N.
The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel.
Biochem. J. 473, 4361-4372 (2016)

Carraretto, L., Teardo, E., Checchetto, V., Finazzi, G., Uozumi, N., and Szabo, I.
Ion channels in plant bioenergetic organelles chloroplast and mitochondria: from molecular identification to function.
Mol. Plant 9, 371-395 (2016)

Checchetto, V., Sgalla, A., Sato, Y., Bergantine, E., Szabo, I. and Uozumi, N.
Involvement of potassium transport systems in the response of Synechocystis PCC 6803 cyanobactria to external pH change, high-intensity light sress and heavy metal stress.
Plant Cell Physiol. 57, 862-877 (2016)

Takito, J., Kimura, J., Kajima, K., Uozumi, N., Watanabe, M., Yokosuka, A., Mimaki, Y., Nakamura, M., and Ohizumi, Y.
Nerve growth factor enhances the CRE-dependent transcriptional activity activated by nobiletin in PC-12 cells.
Can. J. Physiol. Pharm. 94, 728-33 (2016)

Nanatani, K., Shijuku,T, Takano, Y., Zulkifli, L., Yamazaki, Y., Tominaga, A., Souma, S., Onai, K., Morishita, M., Ishiura, M.,  Hagemann, M., Suzuki, I., Maruyama, H., Arai, F., and Uozumi, N.
Comparative analysis of kdp and ktr mutants reveals distinct roles of the potassium transporters in the model cyanobacterium Synechocysis sp. PCC6803.
J.Bacteriol. 197, 676-687 (2015)

Saito, H., Oikawa, T., Hamamoto, S., Ishimaru, Y., Kanamori-Sato, M., Sasaki-Sekimoto, Y., Utsumi, T., Chen, J., Kanno, Y., Masuda, S., Kamiya, Y., Seo, M., Uozumi, N., Ueda, M., and Ohta, H.
The jasmonate-responsive ​GTR1 transporter is required for gibberellin-mediated stamen development in Arabidopsis.
Nature Commun. 6:6095 (2015)

Hamamoto, S., Horie, T., Hauser, F., Deinlein, U., Schroeder J.I. and Uozumi, N.   
HKT transporters mediate salt stress resistance in plants: from structure and function to the field.    

Curr. Opin. Biotechnol
. 32, 113–120 (2015)

Nozoye T., Nagasaka S., Kobayashi T., Sato Y., Uozumi N., Nakanishi H. and Nishizawa N.K.
The phytosiderophore efflux transporter TOM2 is involved in metal transport in rice.
J. Biol. Chem. 290, 27688-99 (2015)

Bashir, K., Ishimaru, Y., Itai, R,N,, Senoura, T,., Takahashi, M., An, G., Oikawa, T., Ueda, M., Sato, A., Uozumi, N., Nakanishi H., Nishizawa, N.K.
Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice.
Plant Mol. Biol. 88, 165-76 (2015)

Ezure, T., Nanatani, K., Sato, Y., Suzuki, S., Aizawa, K., Souma, S., Ito, M., Hohsaka, T., von Heijine, G., Utsumi, T., Abe, K., Ando, E., and Uozumi, N.
A cell-free translocation system using extracts of cultured insect cells to yield functional membrane proteins.
PLOS ONE, 9, e112874 (2014)

Hosoo, Y., Kimura, Y., Nanatani, K., and Uozumi, N.
Molecular cloning and expression analysis of a gene encoding KUP/HAK/KT-type potassium uptake transporter from Cryptomeria japonica.

, 28, 1527-1537 (2014)

Sato, Y., Nanatani, K., Hamamoto, S., Shimizu, M., Takahashi, M., Tabuchi-Kobayashi, M., Mizutani, A.,
Schroeder, J.I., Souma, S, and Uozumi, N.
Defining membrane spanning domains and crucial membrane-localized acidic amino acid residues for K+ transport
of a Kup/HAK/KT-type Escherichia coli potassium transporter.

J. Biochem. 155, 315-323 (2014)

Boccaccio, A., Scholz-Starke, J., Hamamoto, S., Larisch, N., Festa, M., Gutla, P. V. K., Costa, A., Dietrich, P., Uozumi, N., and Carpaneto, A.
The phosphoinositide PI(3,5)P2 mediates activation of mammalian but not plant TPC proteins: functional expression of endolysosomal channels in yeast and plant cells
Cell. Mol. Life Sci. 71, 4275-4283 (2014)

Hamamoto, S., and Uozumi, N.
Organelle-localizated potassium transport system in plants
J. Plant Physiol, 171, 743-747 (2014)

Yamaguchi, T., Hamamoto, S., and Uozumi, N.
Sodium transport system in plant cells.
Frontiers in plant Science, Plant Physiology, 4, 410,1-7 (2013)

Kamal. A.H.M., Cho, K., Choi, J-S., Bae, K-H., Komatus, S., Uozumi, N., and Woo, S.H.
The wheat chloroplastic proteome.
J.Proteomics 93, 326-342(2013)

Nanatani, K., Shijuku, T., Akai, M., Yukutake, Y., Yasui, M., Hamamoto, S., Onai, K., Mrishita, M., Ishiura, M., and Uozumi, N.
Characterization of the role of a mechanosensitive channel in osmotic down shock adaptation in Synechocystis sp. PCC 6803
Channels 7, 229-328 (2013)

Ihara, M., Hamamoto, S., Miyanori, Y., Takeda, M., Kainosho, M., Yabe, I., Uozumi, N., and Yamashita, A.
Molecular bases of multimodal regulation of a fungal transient receptor potential (TRP) channel.
J.Biol.Chem. 288,15303-1537 (2013)

バイオサイエンスとインダストリー 71,234-236 (2013)

Akai, M., Onai, K., Morishita, M., Mino, H., Shijuku, T., Maruyama, H., Arai, F. Itoh, S., Hazama, A., Checchetto, V., Szabò, I., Yukutake, Y., Suematsu, M., Yasui, M., Ishiura, M. and Uozumi, N.
Aquaporin AqpZ 1 is involved in cell volume regulation and sensitivity to osmotic2 stress in Synechocystis sp. PCC 6803       
J. Bacteriol. 194, 6828-6836 (2012)

Checchetto, V., Segalla, A., Allorent, G., Rocca, N. L., Leanza, L., Giacometti, G.M., Uozumi, N., Finazzi, G., Bergantinoa,E., and Szabò, I.
Thylakoid potassium channel is required for efficient photosynthesis in cyanobacteria.
Proc. Natl. Acad. Sci. USA, 109, 11043-11048 (2012)

Sato, Y., Aizawa, K., Edure, T., Ando E., and Uozumi, N.
A simple fed-batch method for transcritption and insect cell-free transition.
J. Biosci. Bioeng. 114,677-679 (2012) 

Kamal, A.H.M., Kun Cho, K., Komatsu, S., and Uozumi, N., Choi, J-S., and Woo, S.H.
Towards an understanding of wheat chloroplasts: a methodical investigation of thylakoid proteome.
Mol. Biol. Rep. 39, 5069-5083 (2012) 

Kamal, A.H.M., Cho, K., Kim, D-E., Uozumi, N., Chung, K-Y., Lee, S.Y., Choi, J-S., Cho, S-W., Shin, C-S., and Woo, S.H.   
Changes in physiology and protein abundance in salt-stressed wheat chloroplasts
Mol. Biol. Rep. 39
, 9059–9074 (2012) 

Bashir, K., Ishimaru, Y., Shimo, H., Kakei, Y., Senoura, T., Takahashi, R., Sato, Y., Sato, Y., Uozumi, N., Nakanishi, H., and Nishizawa, N. K.
Rice phenolics efflux transporter 2 (PEZ2) plays an important role in solubilizing apoplasmic iron.
Soil Sci. Plant Nutr. 57, 803-812 (2012) 

Uozumi, N and Deryer, I.
Structure-function correlates in plant ion channels
In Egelman, E. (ed.)
Comprehensive Biophysics Volume 6 - Channel Proteins
Elsevier BV Amsterdam, 234-245 (2012) 

Ishimaru, Y., Hamamoto, S., Uozumi N., and Ueda, M.
Regulatory mechanism of plant nyctinastic movement: An ion channel-related plant behavior
Plant Electrophysiology 125-142
In Volkov, A. G. (ed.) Spring-Verlag, Berlin Heidelberg (2012) 

Yamaguchi1, T., Uozumi, N., and Horie, T.
Potassium and sodium transporters: Improving salinity tolerance in plants
In Tuteja, N., Gill, S.S., Tiburcio, A. F., Tuteja, R. (ed.)
Improving Crop Resistance to Abiotic Stress, Chapter 23, 523-542 (2012) 

浜本 晋,七谷 圭,佐藤陽子,魚住信之
化学と生物 50 (2) 86-92 (2012)

Dreyer, I and Uozumi N.
Potassium channels in plant cells.
FEBS J. 22, 4293-4303 (2011)
Uozumi N.
Uniquely evolved plant ion channels.
FEBS J. 22, 4261 (2011)
Chanroj, S., Lu, Y., Padmanaban, S., Nanatani, K., Uozumi, N., Rao R. and Sze. H.
Plant-Specific Cation/H+ Exchanger 17 and Homologs Are Endomembrane K+ Transporters with Roles in
protein sorting
J. Biol. Chem. 286, 33931–33941 (2011)
Ishimaru Y, Kakei Y, Shimo, H, Bashir, K, Sato, Y., Sato Y., Uozumi, N., Nakanishi, H., and Nishizawa, NK.
A rice phenolic efflux transporter is essential for solubilizing precipitated apoplasmic iron in the plant stele.
J. Biol. Chem. 286, 24649–24655 (2011)
Akai, M., Onai, K., Kusano, M., Sato, M., Redestig, H., Toyooka, K., Morishita, M., Miyake, H., Hazama, A., Checchetto, V., Szabò, I., Matsuoka, K., Saito, K., Yasui, M., Ishiura, M., and Uozumi, N.
Plasma membrane aquaporin AqpZ protein is essential for glucose metabolism during photomixotrophic growth of Synechocystis sp. PCC 6803.
J. Biol. Chem. 286, 25224–25235 (2011)
Nozoye, T., Nagasaka, S., Kobayashi, T., Takahashi, M., Sato, Y., Sato, Y., Uozumi, N., Nakanishi, H., and Nishizawa, NK.
Phytosiderophore efflux transporters are crucial for iron acquisition in graminaceous plants.
J. Biol. Chem. 286, 5446-5454 (2011)
Ueda, M., Nakamura, Y., Mithoefer, A., Kombrink, E., Boland, W., Hamamoto, S., Uozumi, N., and Tohma, K.
12-Hydroxyjasmonic acid glucoside is a COI1-JAZs independent activator of leaf closing movement in Samanea saman.
Plant Physiol. 155, 1226-1236 (2011)
Lu, Y., Chanroj, S., Zulkifli, L., Johnson, MR., Uozumi, N., Cheung, A., and Sze, H.
Pollen tubes lacking a pair of K+ transporters fail to target ovules in Arabidopsis.
Plant Cell. 23, 81-93 (2011)
植物のNa循環系と耐塩性 日本土壌肥料学雑誌 81 (5) p65-69 (2011)
Zulkifli, L., Akai, M., Yoshikawa, A., Shimojima, M., Ohta, H., Guy HR., and Uozumi, N.
The KtrA and KtrE subunits are required for Na+ dependent K+ uptake by KtrB across the plasma membrane in Synechocystis sp. PCC 6803.
J. Bacteriol. 192, 5063-5070 (2010)
Yamauchi, S., Fusada, N., Hayashi, H., Utsumi, T., Uozumi, N., and Tozawa, Y.
The consensus motif for N-myristoylation of plant proteins in a wheat germ cell-free translation system.
FEBS. J. 277, 3596-3607 (2010)
Voelker, C., Gomez-Porras, J. L., Becker, D., Hamamoto, S., Uozumi, N., Gambale, F., Mueller-Roeber, B., Czempinski, K., and Dreyer, I.
Roles of tandem-pore K+ channels in plants - a puzzle still to be solved.
Plant Biology, 12, 56-63 (2010)
Zanetti, M., Teardo, E., Rocca, N. L., Zulkifli, L., Checchetto, V., Shijuku, T, Sato, Y., Giacometti, G. M., Uozumi, N., Bergantino, E., and Szabò, I.
A novel potassium channel in photosynthetic cyanobacteria.
PLoS ONE, 5, e10118, 1-10 (2010)
Mosimann, M., Goshima, S., Wenzler, Y., Lu¨scher, A., Uozumi, N., and Ma¨ser, P.
Trk/HKT-type K+ transporter from Trypanosoma brucei.
Eukaryotic Cell, 9, 539-546 (2010)
Sato, A., Gambale, F., Dreyer, I., and Uozumi, N.
Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes.
FEBS J. 277, 2318-2328 (2010)
Kobayashi, D., Uozumi, N., Hisamatsu, S., and Yamagami, M.
AtKUP/HAK/KT9, a K+ transporter from Arabidopsis thaliana, mediates Cs+ uptake in Escherichia coli.
Biosci. Biotech. Biochem., 74, 203-205 (2010)
Uozumi, N. and Schroeder J.I.
Ion channels and plant stress: past, present and future 1-22
In Demidchik, V. and Maathuis, F. (ed.)
Ion Channels and Plant Stress Responses
Springer-Verlag Berlin Heidelberg, (2010)
Ito, T., Uozumi, N., Nakamura, T., Takayama, S., Matsuda, N., Aiba, H., Hemmi, H., and Yoshimura, T.
The implication of YggT of Escherichia coli in osmotic regulation.
Biosci. Biotech. Biochem. 73, 2698-2704 (2009)
Sato, A., Sato, Y., Fukao, Y., Fujiwara, M., Umezawa, T., Shinozaki, K., Hibi, T., Taniguchi, M., Miyake, H., Goto, D.B., and Uozumi, N.
Threonine at position 306 of the KAT1 potassium channel is essential for channel activity and is a target site for ABA-activated SnRK2/OST1/SnRK2.6 protein kinase.
Biochem. J. 424, 439-448 (2009)
Yoshida, K., Miki, N., Momonoi, K., Kawachi, M., Katou, K., Okazaki, Y., Uozumi, N., Maeshima, M., and Kondo, T.
Synchrony between flower opening and petal-color change from red to blue in morning glory, Ipomoea tricolor cv. Heavenly Blue.
Proc. Jpn. Acad. Ser. B 85, 187-197 (2009)
Tsunekawa, K., Shijuku, T., Hayashimoto, M., Kojima, T., Onai, K., Morishita, M., Ishiura, M., Kuroda, T., Nakamura, T., Kobayashi, H., Sato, M., Toyooka, K., Matsuoka, K., Omata, T., and Uozumi, N.
Identification and characterization of the Na+/H+ antiporter NhaS3 from the thylakoid membrane of Synechocystis sp. PCC 6803.
J. Biol. Chem. 284, 16513-16521 (2009)
Umemura, K., Satoh, J., Iwata, M., Uozumi, N., Koga, J., Kawano, T., Koshiba, T., Anzai, H., and Mitomi, M.
Contribution of salicylic acid glucosyltransferase, OsSGT1, to chemically-induced disease resistance in rice plants
Plant J. 57, 463-472 (2009).
Hamamoto, S., Yabe, I., and Uozumi, N.
Electrophysiological property of NtTPK1 expressed in yeast tonoplast.
Biosci. Biotech. Biochem., 72, 2785-2787 (2008)
Suga, H., Nagasaki, H., Kondo, T., Okajima, Y., Suzuki, C., Ozaki, N., Arima, H., Yamamoto, T., Ozaki, N., Akai, M., Sato, A., Uozumi, N., Inoue, M., Hasegawa, M., and Oiso, Y.
Novel treatment for lithium induced nephrogenic diabetes insipidus rat model using the Sendai-virus vector carrying aquaporin 2 gene
Endocrinology, 149, 5803-5810 (2008)
Hibi, T., Aoki; S., Oda; K., Munemasa, S., Ozaki, S., Shirai, O., and Uozumi, N.
Purification of the functional plant membrane channel KAT1
Biochem. Biophys. Res. Commun. 374, 465–469 (2008)
Hamamoto, S., Marui, K., Matsuoka, K., Higashi, K., Igarashi, K., Nakagawa, T., Kuroda, T., Mori, Y., Murata, Y., Nakanishi, Y., Maeshima, M., Yabe, I., and Uozumi, N.
Characterization of a tobacco TPK-type K+ channel as a novel tonoplast K+ channel using yeast tonoplasts.
J. Biol. Chem. 283, 1911-1920 (2008)
バイオサイエンスとインダストリー 66, 671-673 (2008)
Kato, N., Akai, M., Zulkifli, L., Matsuda, N., Kato, Y., Goshima, S., Hazama, A., Yamagami, M., Guy, H. R., and Uozumi, N.
Role of positively charged amino acids in the M2D transmembrane helix of Ktr/Trk/HKT-type cation transporters.
Channels 1, 161-171 (2007)
Zhang, L., Sato, Y., Hessa, T., von Heijne, G., Lee, J-K., Kodama, I., Sakaguchi, M., and Uozumi, N.
Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain.
Proc. Natl. Acad. Sci. USA 104, 8263-8268 (2007)
Zulkifli, L. and Uozumi, N.
Mutation of His-157 in the second pore loop drastically reduces the activity of Synechocystis Ktr transporter.
J. Bacteriol. 188, 7985-7987 (2006)
Platten, J.D., Cotsaftis, O., Berthomieu, P., Bohnert, H., Davenport, R.J., Fairbairn, D.J., Horie, T., Leigh, R.A., Lin, H-X., Luan, S., Mäser, P., Pantoja, O., Rodríguez-Navarro, A., Schachtman, D.P., Schroeder, J.I., Sentenac, H., Uozumi, N., Véry, A-A., Zhu, J-K., Dennis, E.S., and Tester, M.
Nomenclature for HKT transporters, key determinants of plant salinity tolerance.
Trends in Plant Sciences 11, 372-374 (2006)
Gambale, F. and Uozumi, N.
Properties of Shaker-type potassium channels in higher plants.
J. Membrane Biol. 210, 1-19 (2006)
Matsuda, N. and Uozumi, N.
Ktr-mediated potassium transport, a major pathway for potassium uptake, is coupled to a proton gradient across the membrane in the Synechocystis sp. PCC6803.
Biosci. Biotech. Biochem. 70, 273-275 (2006)
チャネルタンパク質の膜への組込み様式(イオンチャネル・受容体の構造機能連関研究の新たな潮流 久保義弘監修)
細胞工学25 (3) 秀潤社 264-268 (2006)
Tholema, N., vor der Brüggen, M., Mäser, P., Nakamura, T., Schroeder, J.I., Kobayashi, H., Uozumi, N., and Bakker, E.P.
All four putative selectivity filter glycine residues in KtrB are essential for high affinity and selective K+ uptake by the KtrAB system from Vibrio alginolyticus.
J. Biol. Chem. 280, 41146-41154 (2005)
Sunarpi, Horie, T., Motoda, Jo, Kubo, M., Yang, H., Yoda, K., Horie, R., Chan, W-Y., Leung, H-Y., Hattori, K., Konomi, M., Osumi, M., Yamagami, M., Schroeder, J.I., Uozumi, N.
Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na+ unloading from xylem vessels to xylem parenchyma cells.
Plant J. 44, 928-938 (2005)
Iida, T., Masaharu, K., Uozumi, N., Inui, T., and Imai, K.
Further application of a two-step heparin affinity chromatography method using divalent cations as eluents: Purification and identification of membrane-bound heparin binding proteins from the mitochondrial fraction of HL-60 cells.
J. Chromatography B, 823, 209-212 (2005)
膜電位依存性Kチャネル(イオンチャネル 最前線update 倉智嘉久監修)別冊・医学のあゆみ 
医歯薬出版株式会社 76-81 (2005)
Matsuda, N., Kobayashi, H., Katoh, H., Ogawa, T., Futatsugi, L., Nakamura, T., Bakker, E.P., and Uozumi, N.
Na+-dependent K+ uptake Ktr system from the cyanobacterium Synechocystis sp. PCC 6803 and its role in the early phases of cell adaptation to hyperosmotic shock.
J. Biol. Chem., 279, 54952-54962 (2004)
Zhang, L., Lee, J-K., John, S. A., Uozumi, N., Kadama, I.
Mechanosensitivity of GIRK channels is mediated by PKC-dependent channel-PIP2 interaction.
J. Biol. Chem., 279, 7037 - 7047 (2004)
Ibuki T., Tokida Y., Matsuda N., Czempinski K., Muller-Roeber B., Ona T., and Uozumi N.
Characterization of potassium channels from Arabidopsis thaliana. 167-169 In T. Ona (ed.) Improvement of forest resources for recyclable forest products.
Springer (2004)

Uozumi N.
Large-scale production of hairy root 75-103 In T. Kobayashi (ed.) Recent progress of biochemical and biomedical engineering in Japan II.
Springer (2004)

生化学 76 449-452 (2004)
Umigai, N., Sato, Y., Mizutani, A., Utsumi, T., Sakaguchi, M., and Uozumi, N.
Topogenesis of two transmembrane type K+ channels, Kir 2.1 and KcsA.
J. Biol. Chem., 278, 40373-40384 (2003)
Kato Y., Hazama A., Yamagami M., and Uozumi N.
Addition of a peptide tag at the C terminus of AtHKT1 inhibits its Na+ transport.
Biosci. Biotech. Biochem., 67, (10) 2291-2293 (2003)
Berthomieu, P., Conejero G., Nublat A., Brackenbury W.L. Lambert C., Savio, C., Uozumi, N., Oiki, S., Yamada, K., Cellier, F., Gosti, F., Simonneau, T., Essah, P. A., Tester, M., Very, A-A, Sentenac, H., and Casse, F.
Functional analysis of AtHKT1 in Arabidopsis shows that Na+ recirculation by the phloem is crucial for salt tolerance.
EMBO J., 22, (9) 2004-2014 (2003)
Sato, Y., Sakaguchi, M., Goshima, S., Nakamura, T., and Uozumi, N.
Molecular dissection of the contribution of negatively and positively charged residues in S2, S3, and S4 to the final membrane topology of the voltage sensor in the K+ channel, KAT1.
J. Biol. Chem., 278, 13227-13234 (2003)
Sato, Y., Hosoo, Y., Sakaguchi, M., and Uozumi, N.
Requirement of negative residues, Asp 95 and Asp 105, in S2 on channel function and membrane integration of voltage-dependent K+ channel, KAT1.
Biosci. Biotech. Biochem., 67, 923-926 (2003)
Holtmann, G., Bakker, E. P., Uozumi, N., and Bremerl, E.
KtrAB and KtrCD: two K+ uptake systems in Bacillus subtilis and their role in the adaptation to hypertonicity.
J. Bacteriol., 185, 1289-1298 (2003)
植物カリウムイオン輸送系と生理的役割。(植物の膜輸送システム ポンプ・トランスポーター・チャネル研究の新展開 編者 加藤潔、島崎研一郎、前島正義、三村徹郎) 
植物細胞工学別冊18 秀潤社 40-47 (2003)

K+イオン輸送系の植物成長と塩感受性への役割 (植物の代謝コミュニケーション 植物分子生理学の新展開 編者 杉山達夫、水野猛、長谷俊治、斉藤和季)
蛋白質核酸酵素増刊号48(15)共立出版2052-2060 (2003)
Maser, P., Eckelman, B., Vaidyanathan, R., Fairbain, D. J., Kubo, M., Yamagami, M., Yamaguchi, K., Nishimura, M., Uozumi, N., Robertsin, W., Sussman, M. R., and Schroeder, J. I.
Altered shoot/root Na+ distribution and bifurcating salt sensitivity in Arabidopsis by genetic disruption of the Na+ transporter AtHKT1.
FEBS Letters, 531, 157-16 (2002)
Imai, K., Iida, T., Takano, Y., and Uozumi, N.
Membrane-bound heparin binding proteins from HL-60 cells purified in a 2-step affinity chromatography differentially eluted with divalent cations.
J. Chromatography B, 780, 1-12 (2002)
Maser, P., Hosoo, Y., Goshima, S., Horie, T., Eckelman B., Yamada, K.,Yoshida, K., Bakker, E.P., Shinmyo, A., Oiki, S., Schroeder, J. I., and Uozumi, N.
Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants.
Proc. Natl. Acad. Sci. USA., 99, 6428-6433 (2002)
Sato, Y., Sakaguchi, M., Goshima, S., Nakamura, T., and Uozumi, N.
Integration of Shaker-type K+ channel, KAT1 into the endoplasmic reticulum membrane: Synergistic insertion of voltage sensing segments, S3-S4 and independent insertion of pore-forming segments, S5-P-S6.
Proc. Natl. Acad. Sci. USA., 99, 60-65 (2002)
Uozumi, N., Kato, Y., Matsuda, N., Sato, Y., Mizutani, A.
Structure and function of the Na+/K+ translocating AtHKT1 transporters from plants. Recent Research Developments in Membrane Biology. Research Signpost 119-126 (2002)
Nakamura, T., Fujisaki, Y., Enomoto, H., Nakayama, Y., Takabe, T., Yamaguchi, N., and Uozumi, N.
Residue aspartate-147 from the third transmembrane region of Na+/H+ antiporter NhaB of Vibrio aliginolyticus plays a role in its activity.
J. Bacteriol., 183, 5762-5767 (2001)
Uozumi, N.
E. coli as an expression system for K+ transport systems from plants.
Am. J. Physiol. 281, C733-C739 (2001)
Uozumi, N., Yamada, K., Goshima, S., Ona, T., and Oiki, S.
Sodium blocking induced by a point mutation at the C-terminal end of the pore helix of KAT1 channel.
J. Membrane Biol. 181, 163-170 (2001)
Kato, Y., Sakaguchi, M., Mori, Y., Saito, K., Nakamura, T., Bakker, E. P., Sato, Y., Goshima, S., and Uozumi, N.
Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana Na+/K+ translocating AtHKT1 protein, a member of the superfamily of K+ transporters.
Proc. Natl. Acad. Sci. USA., 98, 6488-6493 (2001)
化学と生物 39(10) 693-697 (2001)

Schroeder, J., Buschmann, P., Eckelman, B., Kim, E., Sussman, M., Uozumi, N., and Maser, P.
Molecular mechanisms of potassium and sodium transport in plants.
In W. J. Horst, M. K. Schenk, A. Bürkert, N. Claassen, H. Flessa, W. B. Frommer, H. Goldbach, H. -W. Olfs, V. Römheld, B. Sattelmacher, U. Schmidhalter, S. Schubert, N. v. Wirén and L. Wittenmayer (ed.) Plant Nutrition 92, 2001
Developments in Plant and Soil Sciences, Springer Netherlands
Kawano, T., Pinontoan, R., Uozumi, N., Morimitsu, Y., Miyake, C., Asada, K., Kolattukudy, P. E., and Muto S.
Aromatic monoamine-Induced immediate oxidative burst leading to an increase in cytosolic Ca2+ concentration in tobacco suspension culture.
Plant Cell Physiol. 41, 1251-1258 (2000)
Kawano T., Pinontoan, R., Uozumi, N., Morimitsu, Y., Miyake, C., Asada, K., and Muto S.
Phenylethylamine-induced generation of reactive oxygen species and ascorbate free radicals in tobacco suspension culture: mechanism for oxidative burst mediating Ca2+ influx.
Plant Cell Physiol. 41, 1259-1266 (2000)
Pinontoan, R., Yuasa, T., Anderca, M.A., Matsuoka, T., Uozumi, N., Mori, H., and Muto, S.
Cloning of cDNA encoding a 66-kDa Ca2K+-dependent protein kinase (CDPK) from Dunaliella tertiolecta (Chlorophyta).
J. Phycol. 36 545-552 (2000)
Kawano, T., Sahashi, N., Uozumi, N., and Muto, S.
Involvement of apoplastic peroxidases in the chitosaccharide-induced immediate oxidative bursts and a cytosolic Ca2+ increase in tobacco suspension culture.
Plant Peroxidase Newsletter 14 (2000)
Mori, I. C., Uozumi, N., and Muto, S.
Phosphorylation of the inward-rectifying potassium channel KAT1 by ABR kinase in Vicia guard cells.
Plant Cell Physiol., 41 (7) 850-856 (2000)
Tasaka, Y., Nakagawa, Y., Sato, C., Mino, M., Uozumi, N., Murata, N., Muto, S., Iida, H.
yam8+, a Schizosaccharomyces pombe gene, is a potential homologue of the Saccharomyces cerevisiae MID1 gene encoding a stretch-activated Ca2+-permeable channel.
Biochem. Biophys. Res. Commun. 269,(1), 265-269 (2000)
Uozumi, N., Kim, E.J., Rubio, F., Yamaguchi, T., Muto, S., Tsuboi, A., Bakker, E.P., Nakamura, T., and Schroeder, J.I.
The Arabidopsis HKT1 gene homologue mediates inward Na+ currents in Xenopus oocytes and Na+ uptake in Saccharomyces cerevisiae.
Plant Physiol. 122 (4) 1249-1259 (2000)
Yamane, T., Tasaki, H., Matsumoto, A., Uozumi, N., and Ashida, T.
Crystallization and preliminary X-ray analysis of beta-amylase from Bacillus polymyxa.
Acta Crystallographica, D55, 898-900 (1999)
Baizabal-Aguirre, V.M., Clemens, S., Uozumi, N., and Schroeder, J.I.
Suppression of inward-rectifying K+ channels KAT1 and AKT2 by dominant negative point mutations in the KAT1 alpha-subunit.
J. Membrane Biol., 167 (2) 119-125 (1999)
Tanaka, N., Uozumi, N., Kobayashi, T.
Genetic transformation of Ajuga reptans. 30-46
In Y. P. S. Bajaj (ed.) Biotechnology in Agriculture and Forestry, vol 45 Springer-Verlag (1999)

中村辰之介 魚住信之 
蛋白質核酸酵素 共立出版 44(13) 1988-1995 (1999)

生物工学会誌 77(5) 187-196 (1999)

生物工学会誌 77(12) 502-505 (1999)
Suehara, K., Nagamori, E., Honda, H., Uozumi, N., and Kobayashi, T. (1998)
Development of rotating-mesh basket type bioreactor for carrot embryo production in immobilized callus system.
J. Chem. Eng. Japan, 31 (4), 613-617. (1998)
Uozumi, N., Nakamura, T., Schroeder, J. I. and Muto, S.
Determination of transmembrane topology of an inward rectifying potassium channel from Arabidopsis thaliana based on functional expression in Escherichia coli.
Proc. Natl. Acad. Sci. USA., 95 (17) 9773-9778 (1998)
Mori, I. C., Iida, H., Tsuji, F. I. , Isobe, M., Uozumi, N., and Muto, S.
Salicylic acid induces a cytosolic Ca2+ elevation in yeast.
Biosci. Biotech. Biochem. 62 (5) 986-989 (1998)
Kawano, T., Sahashi, N., Takahashi,N., Uozumi, N. and Muto, S.
Salicylic acid induces extracellular superoxide generation followed by an increase in cytosolic calcium ion in tobacco suspension culture: The earliest events in salicylic acid signal transduction.
Plant Cell Physiol. 39 (7) 721-730. (1998)
Kim, E. J., Kwak, J. M. Uozumi, N., and Schroeder, J. I.
AtKUP1:An Arabidopsis gene encoding high-affinity potassium transport activity.
Plant Cell, 10 (1) 51-62 (1998)
Honda, H., Hattori, T., Uozumi, N., Kobayashi T., Kato, Y., and Hiraoka, S.
Production of regenerated plantlet using shaking vessel-type bioreactor.
J. Chem. Eng. Japan. 30 (1) 179-182 (1997)
Uozumi, N., Kobayashi, T.
Artificial seed production through hairy root regeneration. 113-122 In P. M. Doran (ed.) Hairy roots culture and applications,
Harwood Academic Publishers (Amsterdam) (1997)
Suehara, K., Takao, S., Nakamura, K., Uozumi, N., and Kobayashi T.
Optimal expression of GUS gene from methyl jasmonate-inducible promoter in high density culture of transformed tobacco cell line BY-2.
J. Ferment. Bioeng. 82 (1) 51-55 (1996)
Uozumi, N., Ohtake, Y., Nakashimada, Y., Morikawa, Y., Tanaka, N., and Kobayashi T. (1996) Efficient regeneration from GUS-transformed Ajuga hairy root.
J. Ferment. Bioeng. 81 (5) 374-385.
Nakashimada, Y., Uozumi, N., and Kobayashi T.
Efficient culture method for production of plantlets from mechanically cut horseradish hairy roots.
J. Ferment. Bioeng. 81 (1) 87-89 (1996)
末原憲一郎 後藤伸介 魚住信之 小林 猛 
化学工学論文集 22(3) 691-694 (1996(原著和文論文)

魚住信之 小林 猛 
植物組織培養における計測 インテリジェント農業ー自動化・知識化のすすめー 
工業調査会 76-89 (1996)
Cao. Y., Ward, J. M., Kelly, W. B., Ichida, A. M., Gaber, R. F., Anderson, J. A., Uozumi, N., Schroeder, J. I., and Crawford. N. M.
Multuple genes, tissue specificity, and expression-dependent modulation contribute to the functional diversity of potassium channels in Arabidopsis thaliana.
Plant Physiol. 109, 1093-1106 (1995)
Uozumi, N., Gassmann, W., Cao. Y., and Schroeder, J. I.
Identification of strong modifications in cation selectivity in an Arabidopsis inward rectifying potassium channel by mutation selection in yeast.
J. Biol. Chem. 270 (41) 24276-24281 (1995)
Uozumi, N., Makino, S., and Kobayashi, T.
20-Hydroxyecdysone production in Ajuga hairy root controlling intracellular phosphate content based on kinetic model.
J. Ferment. Bioeng. 80 (4) 362-368 (1995)
Suehara, K., Kohketsu, K., Uozumi, N., and Kobayashi T.
Efficient production of celery embryos and plantlets released in culture of immobilized gel beads.
J. Ferment. Bioeng. 79 (6) 585-588 (1995)
Nakashimada, Y., Uozumi, N., and Kobayashi, T.
Production of plantlets for use as artificial seeds from horseradish hairy roots fragmented by a blender.
J. Ferment. Bioeng. 79 (5) 458-464 (1995)
Uozumi, N., Kobayashi, T. (1995) Artificial seed production through encapsulation of hairy root and shoot tips. 170 -180 In Y. P. S. Bajaj (ed.)
Biotechnology in Agriculture and Forestry, vol 30 Springer-Verlag
Uozumi, N., Inoue, Y., Yamazaki, K., and Kobayashi, T.
Light activation of expression associated with the tomato rbcS promoter in transformed tobacco cell line BY-2.
J. Biotechnol. 36 (1) 55-62 (1994)
Sota, H., Patthra, A., Kurita, O., Uozumi, N., Honda, H., Iijima, S., and Kobayashi, T.
Molecular cloning of thermostable b-glucosidase gene from a thermophilic anaerobe NA10 and its high expression in Ecsherihia coli.
J. Ferment. Bioeng. 77 (2) 199-201 (1994)
Nakashimada, Y., Uozumi, N., and Kobayashi, T.
Simulation of emergence of root apical meristems in horseradish hairy root by auxin supplementation and its kinetic model.
J. Ferment. Bioeng. 77 (2) 178-182 (1994)
Uozumi, N., Asano, Y., and Kobayashi, T.
Micropropagation of horseradish hairy root by means of adventitious shoot primordia.
Plant Cell Tissue Organ Culture 36 183-190 (1994)
Uozumi, N., Kobayashi, T.
Application of hairy root and bioreactors. 307-338 In D. D. Y. Ryu, S. Furusaki (ed.) Advances in Plant Biotechnology,
Elsevier (1994)
Uozumi, N., Yoshino, T., Shiotani, S., Suehara, K., Arai, F., Fukuda, T. and Kobayashi. T. (1993) Application of image analysis with neural network for plant somatic embryo culture.
J. Ferment. Bioeng. 76 (6) 505-509.
Uozumi, N., Hayashi, A., Ito, T., Patthra, A., Yamashita, I., Iijima, S., and Kobayashi, T.
Secretion of thermophilic bacterial cellobiohydrolase in Saccharomyces cerevisiae.
J. Ferment. Bioeng. 75 (6) 399-404 (1993)
Uozumi, N., Kohketsu, K., Okamoto, A., and Kobayashi, T.
Light dependency in celery somatic embryogenesis and plantlet development in suspension culture.
Plant Tissue Culture Lett. 10 (1) 25-32 (1993)
Ohshima, T., Sugiyama, M., Uozumi, N., Iijima, S., and Kobayashi, T. (1993) Cloning and sequencing of a gene encoding nitrite reductase from Paracoccus denitrificans and expression of the gene in Escherichia coli.
J. Ferment. Bioeng. 76 (2) 88-93.
Uozumi, N., Kohketsu, K., and Kobayashi, T.
Growth and kinetic parameters of Ajuga hairy root in fed-batch culture on monosaccharide medium.
J. Chem. Technol. Biotechnol. 57 (2) 155-161 (1993)
Uozumi, N., Iijima, S., Kobayashi, T.,
Secretion of thermophilic bacterial cellobiohydrolase in Saccharomyces cerevisiae. Genetics, Biochemistry and Ecology of Lignocellulose Degradation, Uni publishers Co., LTD. 408-414 (1993)

小林 猛 魚住信之
食品関連酵素 酵素工学
丸善(株) 91-112 (1993)
Kawabe, T., Ohshima, T., Uozumi, N., Iijima, S., and Kobayashi, T.
Inducible production of recombinant xylose isomerase by Escherichia coli in fed-batch culture.
J. Chem. Eng. Japan. 25 (6) 702-708 (1992)
Uozumi, N., Nakashimada, Y., Kato, Y., and Kobayashi, T.
Production of artificial seed from horseradish hairy root.
J. Ferment. Bioeng. 74 (1) 21-26 (1992)
Uozumi, N., Kato, Y., Nakashimada, Y., and Kobayashi, T.
Excretion of peroxidase from horseradish hairy root in combination with ion supplementation.
Appl. Microbiol. Biotechnol. 37 (5) 560-565 (1992)
小林 猛 魚住信之 
日本機械学会誌 95 45-48 (1992)

小林 猛 魚住信之 
ケミカルエンジニアリング 8月号 18-21 (1992)

化学と工業 45 96-97 (1992)

Uozumi, N.
Functional roles of active-site residues of Bacillus polymyxa b-amylase.
Enzyme Engineering XI, Annals of The New York Academy of Sciences 672 24-28 (1992)

Kobayashi, T., Uozumi, N. Production of artificial seeds. pp. 270-273 In S. Furusaki, I. Endo, R. Matsuno (ed.)
Biochemical Engineering for 2001, Springer-Verlag (1992)
Uozumi, N., Kohketsu, K., Kondo, O., Honda, H., and Kobayashi, T.
Fed-batch culture of hairy root using fructose as a carbon source.
J. Ferment. Bioeng. 72 (6) 457-460 (1991)
Kato, Y., Uozumi, N., Kimura, T., Honda, H., and Kobayashi, T.
Enhancement of peroxidase production and excretion from horseradish hairy roots by light, NaCl and peroxidase-adsorption in situ.
Plant Tissue Culture Lett. 8 (3) 158-165 (1991)
Takekawa, S., Uozumi, N., Tsukagoshi, N., and Udaka, S.
Proteases involved in generation of b- and a-amylases from a large amylase precursor in Bacillus polymyxa.
J. Bacteriol. 173 (21) 6820-6825 (1991)
Uozumi, N., Matsuda, T., Tsukagoshi, N., and Udaka, S.
Structural and functional roles of cysteine residues of Bacillus polymyxa beta-amylase.
Biochemistry 30 (18) 4594-4598 (1991)
日本醗酵工学会誌 第2号 155 (1990)
Uozumi, N., Sakurai, K., Sasaki, T., Takekawa, S., Yamagata, H., Tsukagoshi, N., and Udaka, S.
A single gene directs synthesis of a precursor protein with beta- and alpha-amylase activities in Bacillus polymyxa.
J. Bacteriol. 171 (1) 375-382 (1989)
Kawazu, T., Nakanishi, Y., Uozumi, N., Sasaki, T., Yamagata, H., Tsukagoshi, N., and Udaka, S.
Cloning and nucleotide sequence of the gene coding for enzymatically active fragments of Bacillus polymyxa beta-amylase.
J. Bacteriol. 169 (4) 1564-1570 (1987)

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